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NEK2
| Product Category: | Human lentivirus expressing NEK2 |
| Description: | Premade lentivirus for over-expression of human NEK2 and control, ready to use format. |
| Gene Name: | NIMA related kinase 2 |
| Gene Symbol: | NEK2 |
| Synonyms: | NLK1; RP67; NEK2A; HsPK21; PPP1R111 |
| ACCN: | NM_002497.4 |
| Gene ID: | 4751 |
| Vector: | VP-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
