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| 基因名： | ubiquitin protein ligase E3 component n-recognin 1, UBR1 |
| 别名： | JBS |
| 描述： |
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. |
| 基因ID： |
197131 |
| 规格： |
1× 10^6 |
| 细胞形态： | 上皮样, 贴壁细胞 |
| 传代比例： | 1:3~1:6 |
| 培养体系： |
90% DMEM+10% FBS |
| 冻存液体系： |
50% DMEM+40% FBS+10% DMSO |
| 文档： |
说明书 |
