serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
396488
UniProt ID:
Q02011
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity and cyclic nucleotide binding activity. Involved in forebrain development; regulation of mitochondrial membrane permeability; and response to lipopolysaccharide. Located in several cellular components, including mitochondrial membrane; myelin sheath abaxonal region; and myelin sheath adaxonal region. Used to study carotid stenosis. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 20; multiple sclerosis; and schizophrenia. Orthologous to human CNP (2',3'-cyclic nucleotide 3' phosphodiesterase).
