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ACKR3
| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.062ng/mL |
| Type: | Traditional CXCR7 ELISA kit |
| Synonyms: | ACKR3; RDC1; CMKOR1; GPR159; Chemokine Orphan Receptor 1; Atypical chemokine receptor 3; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog |
| Species: | Human |
| Sample type: | serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 57007 |
| UniProt ID: | P25106 |
| Component: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
