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APBB3
| Detection range: | 0.781-50ng/mL |
| Sensitivity: | 0.34ng/mL |
| Type: | Traditional APBB3 ELISA kit |
| Synonyms: | APB-B3; SRA; FE65L2; FE65-L2; Fe65L2 isoform 484; Alzheimers beta-amyloid interaction protein; Amyloid beta (A4) protein-binding, family B, member 3, isoform CRA_g |
| Species: | Human |
| Sample type: | tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 10307 |
| UniProt ID: | O95704 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.
