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CASP6
| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.069ng/mL |
| Type: | Traditional CASP6 ELISA kit |
| Synonyms: | MCH2; Cysteinyl Aspartate Specific Proteinases 6; Caspase 6,Apoptosis-Related Cysteine Peptidase; Apoptotic protease Mch-2 |
| Species: | Human |
| Sample type: | serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 839 |
| UniProt ID: | P55212 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
This gene CAPZB encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
