CCL27; ILC; SCYA27; ALP; Skinkine; ESkine; PESKY; CTAK; Chemokine(C-C-Motif)ligand 27; Small Inducible Cytokine Subfamily A Member 27; IL-11 R-alpha-locus chemokine
Species:
Human
Sample type:
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
16 months
Gene ID:
10850
UniProt ID:
Q9Y4X3
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Standard Diluent 1×10 mL
5. Detection Solution A 1×6 mL
6. Detection Solution B 1×6 mL
7. TMB Substrate 1×4.5 mL
8. Stop Solution: 1×3 mL
9. Wash Buffer (30× concentrate): 1×10 mL
Background
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.
