Sidebar
ERN1
| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.071ng/mL |
| Type: | Traditional ERN1 ELISA kit |
| Synonyms: | IRE1; IRE1P; Serine/Threonine-Protein Kinase/Endoribonuclease IRE1; Inositol-requiring protein 1; Ire1-alpha; Serine/threonine-protein kinase; Endoribonuclease |
| Species: | Human |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 2081 |
| UniProt ID: | O75460 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables ATP binding activity; MAP kinase activity; and scaffold protein binding activity. Involved in several processes, including arachidonate metabolic process; decidualization; and peptidyl-serine phosphorylation. Located in caveola; cytoplasm; and nucleoplasm. Part of protein-containing complex. Used to study several diseases, including alcohol dependence; cocaine abuse; drug dependence (multiple); gastric ulcer; and middle cerebral artery infarction. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in Parkinson's disease; carcinoma (multiple); and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3).
