RNA helicase-DEAD box protein 116(RLR-2); Murabutide down-regulated protein; Melanoma differentiation-associated protein 5(MDA-5); Interferon-induced with helicase C domain protein 1; RNA helicase-DEAD box protein 116; Clinically amyopathic dermatomyositis autoantigen 140 kDa(CADM-140 autoantigen); Helicase with 2 CARD domains(Helicard)
Species:
Human
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
64135
UniProt ID:
Q9BYX4
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
The gene PRLR encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
