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IL36A
| Detection range: | 15.6-1000pg/mL |
| Sensitivity: | 5.1pg/mL |
| Type: | Traditional IL1ε ELISA kit |
| Synonyms: | IL1F6; IL36a; FIL1; FIL1(EPSILON); FIL1E; IL-1F6; IL1(EPSILON); Interleukin 36, Alpha; Interleukin 1 Family, Member 6 |
| Species: | Human |
| Sample type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 27179 |
| UniProt ID: | Q9UHA7 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
