| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.054ng/mL |
| Type: | Traditional JUP ELISA kit |
| Synonyms: | DP3; gCat; G-Cat; CTNNG; DPIII; PDGB; PKGB; Gamma Catenin; Desmoplakin III; Desmoplakin-3 |
| Species: | Human |
| Sample type: | tissue homogenates, cell lysates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 3728 |
| UniProt ID: | P14923 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables chromatin binding activity and transcription cis-regulatory region binding activity. Involved in cellular response to anisomycin and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including circulatory system development; eyelid development in camera-type eye; and positive regulation of cell population proliferation. Located in nucleus. Part of transcription factor AP-1 complex and transcription repressor complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; long bone; and sensory organ. Used to study psoriasis and pulmonary emphysema. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human JUN (Jun proto-oncogene, AP-1 transcription factor subunit).
