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KLK12
| Detection range: | 15.6-1000ng/mL |
| Sensitivity: | 7.14ng/mL |
| Type: | Traditional KLK12 ELISA kit |
| Synonyms: | KLK-L5; KLKL5; Kallikrein-Related Peptidase 12; Kallikrein-like protein 5 |
| Species: | Human |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Competitive inhibition |
| Shelf life: | 12 months |
| Gene ID: | 43849 |
| UniProt ID: | Q9UKR0 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
