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LCN1
| Detection range: | 78.1-5000pg/mL |
| Sensitivity: | 29pg/mL |
| Type: | Traditional LCN1 ELISA kit |
| Synonyms: | TP; PMFA; VEGP; Tlc; Tear Prealbumin; Tear lipocalin; Protein Migrating Faster Than Albumin; Von Ebner Gland Protein |
| Species: | Human |
| Sample type: | serum, plasma, saliva, tears or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 3933 |
| UniProt ID: | P31025 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9.
