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NR1D2
| Detection range: | 0.312-20ng/mL |
| Sensitivity: | 0.128ng/mL |
| Type: | Traditional NR1D2 ELISA kit |
| Synonyms: | HZF2; BD73; EAR-1r; RVR; Rev-ErbA Beta; Orphan nuclear hormone receptor BD73; Rev-erb alpha-related receptor; V-erbA-related protein 1-related |
| Species: | Human |
| Sample type: | tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 9975 |
| UniProt ID: | Q14995 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene.
