Human Sestrin 1 (SESN1) ELISA Kit (96T)

Human Sestrin 1 (SESN1) ELISA Kit (96T)

Catalog #: TD4243
Availability: In Stock
¥649.00
Detection range: 0.156-10ng/mL    
Sensitivity: 0.064ng/mL    
Type: Traditional SESN1 ELISA kit    
Synonyms: SEST1; PA26; p53-regulated protein PA26
Species: Human
Sample type: tissue homogenates or other biological fluids.
Experimental method: Sandwich
Shelf life: 12 months
Gene ID: 27244
UniProt ID: Q9Y6P5
Components: 1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL




Background

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression.

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