Lentivirus Fto (5×200 μl)

Lentivirus Fto (5×200 μl)

Catalog #: M2528
Availability: In Stock
¥899.00
Product Category: Mouse lentivirus expressing Fto    
Description: Premade lentivirus for over-expression of mouse Fto and control, ready to use format.
Gene Name: FTO alpha-ketoglutarate dependent dioxygenase
Gene Symbol: Fto
Synonyms: mKIAA1752
ACCN: NM_011936.2
Gene ID: 26383
Vector: PDS279_pL-CMV-GFP-ccdB-puro
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

Enables broad specificity oxidative DNA demethylase activity and oxidative RNA demethylase activity. Involved in several processes, including DNA alkylation repair; RNA repair; and regulation of respiratory system process. Located in nucleus. Is expressed in several structures, including alimentary system; cerebral cortex; gonad; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic neuropathy; nuclear senile cataract; renal cell carcinoma (multiple); and type 2 diabetes mellitus. Orthologous to human FTO (FTO alpha-ketoglutarate dependent dioxygenase).

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