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SOCS5
| Product Category: | Human lentivirus expressing SOCS5 |
| Description: | Premade lentivirus for over-expression of human SOCS5 and control, ready to use format. |
| Gene Name: | suppressor of cytokine signaling 5 |
| Gene Symbol: | SOCS5 |
| Synonyms: | CIS6; CISH6; Cish5; SOCS-5 |
| ACCN: | NM_014011.5 |
| Gene ID: | 9655 |
| Vector: | VP001-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.
