serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
11606
UniProt ID:
P11859
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables receptor ligand activity; type 1 angiotensin receptor binding activity; and type 2 angiotensin receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; aldosterone secretion; and angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure. Acts upstream of or within several processes, including positive regulation of intracellular signal transduction; positive regulation of metabolic process; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is active in extracellular region. Is expressed in several structures, including axial skeleton; central nervous system; foregut mesenchyme; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen).
