tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
11689
UniProt ID:
P48999
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables arachidonate 5-lipoxygenase activity. Involved in several processes, including leukotriene A4 biosynthetic process; negative regulation of angiogenesis; and regulation of cellular response to stress. Acts upstream of or within leukotriene biosynthetic process and leukotriene production involved in inflammatory response. Located in cytoplasm and nucleus. Is expressed in limb long bone and small intestine epithelium. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma (multiple); pancreatic cancer; and pulmonary tuberculosis. Orthologous to human ALOX5 (arachidonate 5-lipoxygenase).
