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Atp4b
| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.066ng/mL |
| Type: | Traditional ATP4β ELISA kit |
| Synonyms: | Proton pump beta chain; Gastric H(+)/K(+) ATPase subunit beta |
| Species: | Mouse |
| Sample type: | tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 11945 |
| UniProt ID: | P50992 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables several functions, including ATP binding activity; P-type calcium transporter activity; and PDZ domain binding activity. Involved in neural retina development. Located in apical plasma membrane; dendritic spine membrane; and neuronal cell body membrane. Is active in several cellular components, including GABA-ergic synapse; parallel fiber to Purkinje cell synapse; and synaptic membrane. Biomarker of brain infarction. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 82 and autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2).
