tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
12775
UniProt ID:
P47774
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables C-C chemokine receptor activity. Involved in negative regulation of innate immune response. Acts upstream of or within inflammatory response; leukocyte chemotaxis; and myeloid cell differentiation. Predicted to be located in neuronal cell body and plasma membrane. Predicted to be active in cytoplasm and external side of plasma membrane. Is expressed in several structures, including aorta-gonad-mesonephros; extraembryonic component; limb; and liver. Used to study Coronavirus infectious disease. Human ortholog(s) of this gene implicated in allergic contact dermatitis and rheumatoid arthritis. Orthologous to human CCR1 (C-C motif chemokine receptor 1).
