K35; Cell division protein kinase 8; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8
Species:
Mouse
Sample type:
tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
264064
UniProt ID:
Q8R3L8
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Predicted to enable protein kinase binding activity; protein tyrosine phosphatase activity; and protein-folding chaperone binding activity. Predicted to be involved in several processes, including mitotic cell cycle phase transition; positive regulation of cell cycle G2/M phase transition; and positive regulation of cholangiocyte proliferation. Located in cytoplasm and nucleus. Is expressed in several structures, including adrenal gland; central nervous system; early embryo; gonad; and gut. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease; cervical cancer; prostate cancer; and urinary bladder cancer. Orthologous to human CDC25A (cell division cycle 25A).
