Cellular Repressor Of E1A Stimulated Genes 1; CREG1
Species:
Mouse
Sample type:
tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
433375
UniProt ID:
O88668
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables histone H3T11 kinase activity. Involved in negative regulation of gene expression, epigenetic. Acts upstream of or within several processes, including DNA damage checkpoint signaling; G2/M transition of mitotic cell cycle; and inner cell mass cell proliferation. Located in chromatin; nucleus; and replication fork. Is expressed in several structures, including adrenal medulla; brain; early conceptus; gonad; and gut. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human CHEK1 (checkpoint kinase 1).
