| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.059ng/mL |
| Type: | Traditional DCLK1 ELISA kit |
| Synonyms: | DCDC3A; DCLK; DCAMKL1; Doublecortin And CaM Kinase-Like 1; Doublecortin domain-containing protein 3A; Doublecortin-like and CAM kinase-like 1 |
| Species: | Mouse |
| Sample type: | tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 13175 |
| UniProt ID: | Q9JLM8 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable actin filament binding activity; cytoskeletal motor inhibitor activity; and profilin binding activity. Involved in several processes, including positive regulation of dendritic spine morphogenesis; positive regulation of receptor localization to synapse; and positive regulation of synaptic plasticity. Acts upstream of or within several processes, including cell communication by chemical coupling; cell communication by electrical coupling; and maintenance of protein location in cell. Located in several cellular components, including actin cytoskeleton; gap junction; and growth cone. Is active in several cellular components, including postsynaptic cytosol; postsynaptic density; and postsynaptic membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Orthologous to human DBN1 (drebrin 1).
