serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
13849
UniProt ID:
Q9D379
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Predicted to enable enzyme binding activity; ferrous iron binding activity; and hypoxia-inducible factor-proline dioxygenase activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; regulation of modification of postsynaptic structure; and regulation protein catabolic process at postsynapse. Acts upstream of or within heart morphogenesis and labyrinthine layer development. Is active in glutamatergic synapse and postsynaptic density. Is expressed in central nervous system; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in familial erythrocytosis 3; polycythemia; and renal cell carcinoma. Orthologous to human EGLN1 (egl-9 family hypoxia inducible factor 1).
