serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
14377
UniProt ID:
P35576
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables several functions, including cytoskeletal protein binding activity; protein tyrosine kinase activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of dendritic spine maintenance; positive regulation of tyrosine phosphorylation of STAT protein; and reelin-mediated signaling pathway. Acts upstream of or within several processes, including activated T cell proliferation; negative regulation of protein metabolic process; and nervous system development. Located in several cellular components, including actin filament; membrane raft; and postsynaptic density. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study skin disease and skin squamous cell carcinoma. Human ortholog(s) of this gene implicated in Alzheimer's disease; alcohol dependence; and schizophrenia. Orthologous to human FYN (FYN proto-oncogene, Src family tyrosine kinase).
