| Detection range: | 0.781-50ng/mL |
| Sensitivity: | 0.31ng/mL |
| Type: | Traditional GAD1 ELISA kit |
| Synonyms: | GAD67; SCP; 67 kDa glutamic acid decarboxylase; Glutamate decarboxylase 67 kDa isoform |
| Species: | Mouse |
| Sample type: | tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 14415 |
| UniProt ID: | P48318 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable GABA-gated chloride ion channel activity; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Involved in inhibitory synapse assembly. Located in several cellular components, including dendrite; inhibitory synapse; and neuronal cell body. Is active in GABA-ergic synapse and postsynaptic specialization membrane. Is expressed in central nervous system and lens. Human ortholog(s) of this gene implicated in alcohol dependence; alcohol use disorder; autistic disorder; and developmental and epileptic encephalopathy 78. Orthologous to human GABRA2 (gamma-aminobutyric acid type A receptor subunit alpha2).
