| Detection range: | 78.1-5000pg/mL |
| Sensitivity: | 32.4pg/mL |
| Type: | Traditional HSPG2 ELISA kit |
| Synonyms: | PLC; PRCAN; SJA; SJS; SJS1; Perlecan; Endorepellin; Schwartz-Jampel Syndrome 2; Basement membrane-specific heparan sulfate proteoglycan core protein |
| Species: | Mouse |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 15530 |
| UniProt ID: | Q05793 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study autosomal dominant distal hereditary motor neuronopathy 2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and autosomal dominant distal hereditary motor neuronopathy 2. Orthologous to human HSPB8 (heat shock protein family B (small) member 8).
