CD121a; CD121-A; IL1-R1; IL1R; IL1RA; P80; CD121 Antigen-Like Family Member A; Interleukin-1 Receptor Alpha
Species:
Mouse
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
16177
UniProt ID:
P13504
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables interleukin-1 binding activity; interleukin-1 receptor activity; and protease binding activity. Involved in interleukin-1-mediated signaling pathway. Acts upstream of or within several processes, including cytokine-mediated signaling pathway; positive regulation of interleukin-1-mediated signaling pathway; and positive regulation of neutrophil extravasation. Located in external side of plasma membrane. Is expressed in aorta-gonad-mesonephros; brain; liver; spleen; and uterus. Used to study Sjogren's syndrome and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in chronic recurrent multifocal osteomyelitis; systemic scleroderma; and type 1 diabetes mellitus. Orthologous to human IL1R1 (interleukin 1 receptor type 1).
