CD309; FLK1; VEGFR; KDR; A Type III Receptor Tyrosine Kinase; Kinase Insert Domain Receptor; Kinase Insert Domain Receptor; Fetal Liver Kinase-1
Species:
Mouse
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
16 months
Gene ID:
16542
UniProt ID:
Q8VCD0
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Standard Diluent 1×10 mL
5. Detection Solution A 1×6 mL
6. Detection Solution B 1×6 mL
7. TMB Substrate 1×4.5 mL
8. Stop Solution: 1×3 mL
9. Wash Buffer (30× concentrate): 1×10 mL
Background
Enables coreceptor activity; growth factor binding activity; and vascular endothelial growth factor receptor activity. Involved in several processes, including circulatory system development; peptidyl-tyrosine autophosphorylation; and positive regulation of BMP signaling pathway. Acts upstream of or within several processes, including positive regulation of cell population proliferation; post-embryonic camera-type eye morphogenesis; and vasculature development. Located in several cellular components, including cell junction; endosome; and external side of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including adhesions of uterus; artery disease (multiple); gastrointestinal system cancer (multiple); macular degeneration (multiple); and pancreatic cancer (multiple). Orthologous to human KDR (kinase insert domain receptor).
