INrf2; KLHL19; Cytosolic inhibitor of Nrf2; Kelch-like protein 19
Species:
Mouse
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
50868
UniProt ID:
Q9Z2X8
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Contributes to G-protein activated inward rectifier potassium channel activity. Predicted to be involved in cardiac conduction; potassium ion import across plasma membrane; and regulation of monoatomic ion transmembrane transport. Predicted to be located in T-tubule and external side of plasma membrane. Predicted to be part of I(KACh) inward rectifier potassium channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; heart; intestine; and liver lobe. Human ortholog(s) of this gene implicated in atrial fibrillation; long QT syndrome 13; and primary hyperaldosteronism. Orthologous to human KCNJ5 (potassium inwardly rectifying channel subfamily J member 5).
