serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
16816
UniProt ID:
P16301
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables fibroblast growth factor binding activity and fibroblast growth factor receptor binding activity. Acts upstream of or within several processes, including determination of adult lifespan; energy reserve metabolic process; and positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway. Predicted to be located in extracellular region and membrane. Is expressed in brain; femur; and metanephros. Used to study hyperphosphatemic familial tumoral calcinosis and pulmonary emphysema. Human ortholog(s) of this gene implicated in coronary artery disease; intracranial embolism; and spondylosis. Orthologous to human KL (klotho).
