| Detection range: | 3.12-200pg/mL |
| Sensitivity: | 1.47pg/mL |
| Type: | Traditional MSP ELISA kit |
| Synonyms: | MST1; HGFL; NF15S2; Hepatocyte Growth Factor-Like Protein; Macrophage Stimulating 1 |
| Species: | Mouse |
| Sample type: | serum, plasma or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 15235 |
| UniProt ID: | P26928 |
| Component: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables several functions, including DNA binding activity; histone acetyltransferase binding activity; and transcription coactivator binding activity. Involved in several processes, including nuclear receptor-mediated corticosteroid signaling pathway; positive regulation of transcription by RNA polymerase II; and response to mineralocorticoid. Located in cytoplasm and nucleus. Is active in glutamatergic synapse; postsynaptic density, intracellular component; and presynaptic active zone cytoplasmic component. Used to study alcohol use disorder; morphine dependence; and polycystic ovary syndrome. Biomarker of alcohol dependence; fetal alcohol spectrum disorder; obesity; and steatotic liver disease. Human ortholog(s) of this gene implicated in autosomal dominant pseudohypoaldosteronism type 1 and pseudohypoaldosteronism. Orthologous to human NR3C2 (nuclear receptor subfamily 3 group C member 2).
