MYOD1; PUM; MYF3; bHLHc1; Myoblast Determination Protein 1; Myogenic Factor 3; Class C basic helix-loop-helix protein 1
Species:
Mouse
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
17927
UniProt ID:
P10085
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables ATP-dependent histone chaperone activity; signaling adaptor activity; and signaling receptor binding activity. Involved in several processes, including cellular response to oxidised low-density lipoprotein particle stimulus; positive regulation of macromolecule biosynthetic process; and response to bacterium. Acts upstream of or within several processes, including establishment of endothelial intestinal barrier; regulation of cytokine production; and response to bacterium. Located in cytosol and plasma membrane. Is expressed in several structures, including brain; intestine; and spleen. Used to study Alzheimer's disease; Coronavirus infectious disease; Sjogren's syndrome; and monoclonal gammopathy of uncertain significance. Human ortholog(s) of this gene implicated in colorectal cancer (multiple); hepatocellular carcinoma; lung cancer (multiple); lymphoma (multiple); and primary immunodeficiency disease. Orthologous to human MYD88 (MYD88 innate immune signal transduction adaptor).
