serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
12735
UniProt ID:
P97400
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables cytokine activity. Involved in cell surface receptor signaling pathway via STAT; positive regulation of B cell activation; and positive regulation of astrocyte differentiation. Acts upstream of or within B cell differentiation and cell surface receptor signaling pathway via JAK-STAT. Predicted to be located in extracellular space. Predicted to be part of CNTFR-CLCF1 complex and CRLF-CLCF1 complex. Predicted to be active in extracellular region. Is expressed in several structures, including alimentary system; central nervous system; lung; metanephros; and skeletal musculature. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 2. Orthologous to human CLCF1 (cardiotrophin like cytokine factor 1).
