tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
18181
UniProt ID:
Q9WU00
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables several functions, including heat shock protein binding activity; receptor tyrosine kinase binding activity; and transcription coactivator activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; regulation of synaptic plasticity; and response to glucocorticoid. Located in dendritic spine and nucleus. Part of protein-containing complex. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Used to study several diseases, including alcohol dependence; alcohol use disorder; alcoholic neuropathy; cocaine abuse; and morphine dependence. Biomarker of several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; brain disease (multiple); cocaine dependence; and cognitive disorder (multiple). Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; anorexia nervosa; heroin dependence; lung disease (multiple); and nicotine dependence. Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1).
