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Ogn
| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.066ng/mL |
| Type: | Traditional OGN ELISA kit |
| Synonyms: | OIF; SLRR3A; Mimecan Proteoglycan; Osteoinductive Factor |
| Species: | Mouse |
| Sample type: | tissue homogenates, cell lysates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 18295 |
| UniProt ID: | Q62000 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity and microtubule binding activity. Acts upstream of or within base-excision repair. Located in mitochondrion and nucleus. Is expressed in junctional zone and labyrinthine zone. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; artery disease (multiple); carcinoma (multiple); eye disease (multiple); and reproductive organ cancer (multiple). Orthologous to human OGG1 (8-oxoguanine DNA glycosylase).
