Roof plate-specific spondin-3; Nucleopondin; Cabriolet; Cysteine-rich and single thrombospondin domain-containing protein 1(Cristin-1)
Species:
Mouse
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
72780
UniProt ID:
Q2TJ95
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables frizzled binding activity; protein domain specific binding activity; and receptor ligand activity. Involved in several processes, including heart development; neuron differentiation; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including embryonic morphogenesis; morphogenesis of an epithelium; and reproductive structure development. Located in cell surface and extracellular matrix. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; limb; and sensory organ. Used to study Robinow syndrome. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A).
