ATOD4; CIS3; Cish3; MGC71791; SOCS-3; SSI-3; SSI3; Cytokine-inducible SH2 protein 3; STAT-induced STAT inhibitor 3
Species:
Mouse
Sample type:
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
12702
UniProt ID:
O35718
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables miRNA binding activity and phosphotyrosine residue binding activity. Involved in cellular response to interleukin-17. Acts upstream of or within several processes, including branching involved in labyrinthine layer morphogenesis; cellular response to leukemia inhibitory factor; and negative regulation of insulin receptor signaling pathway. Predicted to be located in cytosol. Predicted to be active in cytoplasmic side of plasma membrane. Is expressed in several structures, including extraembryonic component; liver; placenta; retina; and spleen. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SOCS3 (suppressor of cytokine signaling 3).
