| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.056ng/mL |
| Type: | Traditional TRPV1 ELISA kit |
| Synonyms: | VR1; OTRPC1; Vanilloid Receptor Subtype 1; Capsaicin receptor; Osm-9-like TRP channel 1; Vanilloid receptor 1 |
| Species: | Mouse |
| Sample type: | tissue homogenates, cell lysates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 193034 |
| UniProt ID: | Q704Y3 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables calcium channel activity; identical protein binding activity; and temperature-gated ion channel activity. Involved in detection of temperature stimulus involved in sensory perception of pain; monoatomic ion transmembrane transport; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including diet induced thermogenesis; fever generation; and sensory perception of chemical stimulus. Located in neuron projection and plasma membrane. Is active in GABA-ergic synapse and postsynaptic membrane. Is expressed in central nervous system; cochlea; dorsal root ganglion; and eye. Human ortholog(s) of this gene implicated in migraine. Orthologous to human TRPV1 (transient receptor potential cation channel subfamily V member 1).
