N1-Methyl-Pseudouridine (1 g)

N¹-Methyl-Pseudouridine is a modified nucleoside used for enhancing mRNA translation. Incorporation of N1-Methylpseudouridine into mRNA turns off the immune/eIF2α phosphorylation-dependent inhibition of translation, and increases ribosome pausing and density on the mRNA, thus dramatically facilitating the translation process. N¹-Methylpseudouridine outperforms several other modified nucleosides (e.g. 5-Methylcytidine) and corresponding combinations in terms of translation capacity.
 

Specifications

1. Formal Name: N¹-Methyl-Pseudouridine

2. CAS Number: 13860-38-3

3. Molecular Formula: C₁₀H₁₄N₂O₆

4. Molecular Weight: 258.23

5. Purity: 99.5%
 

Component

1. N1-Methyl-Pseudouridine: 1 g
 

Storage

Store at -20°C
 

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