| Detection range: | 0.156-10ng/mL |
| Sensitivity: | 0.051ng/mL |
| Type: | Traditional AGTR2 ELISA kit |
| Synonyms: | AT2R; AT2-R; ATGR2; AT2; MRX88 |
| Species: | Rat |
| Sample type: | tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 24182 |
| UniProt ID: | P35351 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables angiotensin type II receptor activity. Involved in several processes, including cellular response to dexamethasone stimulus; positive regulation of branching involved in ureteric bud morphogenesis; and regulation of secretion. Located in perinuclear region of cytoplasm. Used to study chronic kidney disease; congenital diaphragmatic hernia; glomerulonephritis (multiple); hypertension (multiple); and meconium aspiration syndrome. Biomarker of several diseases, including asthma; congestive heart failure; glomerulosclerosis (multiple); hypertension; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypoglycemia; intellectual disability; and vesicoureteral reflux. Orthologous to human AGTR2 (angiotensin II receptor type 2).
