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Aldoc
| Detection range: | 0.625-40ng/mL |
| Sensitivity: | 0.283ng/mL |
| Type: | Traditional ALDOC ELISA kit |
| Synonyms: | ALDO-C; ALDC; ALD-C; Fructose-bisphosphate aldolase C; Brain-type aldolase |
| Species: | Rat |
| Sample type: | serum, plasma or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 24191 |
| UniProt ID: | P09117 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables fructose-bisphosphate aldolase activity and phosphatidylcholine binding activity. Involved in several processes, including cellular response to insulin stimulus; response to fructose; and response to interleukin-6. Located in perinuclear region of cytoplasm; rough endoplasmic reticulum membrane; and smooth endoplasmic reticulum membrane. Used to study type 2 diabetes mellitus. Biomarker of liver benign neoplasm; peritonitis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B).
