serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Competitive inhibition
Shelf life:
12 months
Gene ID:
58812
UniProt ID:
Q9R0R3
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables NF-kappaB binding activity and RNA endonuclease activity. Involved in several processes, including cellular response to Thyroid stimulating hormone; cellular response to cAMP; and positive regulation of G1/S transition of mitotic cell cycle. Part of transcription regulator complex. Biomarker of brain ischemia; hepatocellular carcinoma; lung disease; and status epilepticus. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1).
