AQP-CD; WCH-CD; ADH water channel; Aquaporin-CD; Collecting duct water channel protein; Water channel protein for renal collecting duct
Species:
Rat
Sample type:
tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
25386
UniProt ID:
P34080
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables PDZ domain binding activity; actin binding activity; and water transmembrane transporter activity. Involved in several processes, including actin filament depolymerization; cellular response to water deprivation; and response to glucagon. Located in several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and trans-Golgi network. Part of protein-containing complex. Used to study diabetes insipidus. Biomarker of hypertension and nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus and nephrogenic diabetes insipidus type 2. Orthologous to human AQP2 (aquaporin 2).
