tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
64044
UniProt ID:
Q9JHX4
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables cysteine-type endopeptidase activity; death receptor binding activity; and tumor necrosis factor receptor binding activity. Involved in several processes, including response to anesthetic; response to estradiol; and response to lipopolysaccharide. Located in cell body and cytosol. Part of CD95 death-inducing signaling complex. Used to study epilepsy and pre-malignant neoplasm. Biomarker of several diseases, including brain disease (multiple); heart disease (multiple); kidney disease (multiple); lung disease (multiple); and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including autoimmune lymphoproliferative syndrome type 2B; breast cancer; endocrine gland cancer (multiple); esophagus adenocarcinoma; and lung cancer. Orthologous to human CASP8 (caspase 8).
