tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
25166
UniProt ID:
P43527
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables calmodulin binding activity and calmodulin-dependent protein phosphatase activity. Involved in several processes, including cellular response to glucose stimulus; negative regulation of insulin secretion; and protein import into nucleus. Located in slit diaphragm. Part of calcineurin complex. Is active in synapse. Biomarker of kidney disease. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 91. Orthologous to human PPP3CA (protein phosphatase 3 catalytic subunit alpha).
