| Detection range: | 15.6-1000pg/mL |
| Sensitivity: | 4.58pg/mL |
| Type: | Traditional CRH ELISA kit |
| Synonyms: | CRF; Corticotropin Releasing Factor; Corticoliberin |
| Species: | Rat |
| Sample type: | serum, plasma or other biological fluids. |
| Experimental method: | Competitive inhibition |
| Shelf life: | 12 months |
| Gene ID: | 81648 |
| UniProt ID: | P01143 |
| Component: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable several functions, including complement receptor activity; immunoglobulin receptor binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including B cell activation; negative regulation of complement activation, classical pathway; and type I interferon-mediated signaling pathway. Predicted to act upstream of or within with a negative effect on complement activation, alternative pathway. Predicted to act upstream of or within several processes, including cellular response to lipopolysaccharide; immunoglobulin mediated immune response; and skeletal system development. Located in cell surface and extracellular space. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7; nasopharynx carcinoma; and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2).
