serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
306748
UniProt ID:
Q8K453
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables BH domain binding activity; heat shock protein binding activity; and protein-folding chaperone binding activity. Involved in several processes, including mitochondrion organization; response to anesthetic; and response to ischemia. Located in cytosol; mitochondrial outer membrane; and perinuclear region of cytoplasm. Used to study brain glioma; endometriosis; morphine dependence; and pre-malignant neoplasm. Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); heart disease (multiple); lung disease (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator).
