FOX-O1; FKH1; FKHR; FOXO1A; Forkhead Homolog In Rhabdomyosarcoma
Species:
Rat
Sample type:
tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
84482
UniProt ID:
G3V7R4
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including positive regulation of osteoclast differentiation; response to muscle stretch; and skeletal muscle cell differentiation. Located in endoplasmic reticulum and nucleus. Part of transcription factor AP-1 complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and limb. Orthologous to human FOS (Fos proto-oncogene, AP-1 transcription factor subunit).
